Article

Airway Basal Cells Show Regionally Distinct Potential to Undergo Metaplastic Differentiation

2022-05-05

Abstract excerpt

<h4>SUMMARY</h4> Basal cells are multipotent stem cells of a variety of organs, and in the lung are known as crucial components of the airway epithelium. However, it remains unclear how diverse basal cells are and whether distinct subpopulations respond differently to airway challenges. Using single cell RNA-sequencing and functional approaches, we report a significant and previously underappreciated degree of he...

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Literature Corpus work: de685430-f7f9-568e-b441-89f2bb0392b7
DOI: 10.1101/2022.05.04.490677

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