Article
Population genomics and the evolution of virulence in the fungal pathogen <i>Cryptococcus neoformans</i>
2017-03-19
Abstract excerpt
Cryptococcus neoformans is an opportunistic fungal pathogen that causes approximately 625,000 deaths per year from nervous system infections. Here, we leveraged a unique, genetically diverse population of C. neoformans from sub-Saharan Africa, commonly isolated from mopane trees, to determine how selective pressures in the environment coincidentally adapted C. neoformans for human virulence. Genome sequencing an...
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Identifiers and source
- Literature Corpus work
- f0524610-d28d-5079-a20f-045c7ff97753
- DOI
- 10.1101/118323
