Article

Genomic variation during culture-adaptation of genetically complex <i>Plasmodium falciparum</i> clinical isolates

2022-09-15

Abstract excerpt

Experimental studies on the biology of malaria parasites have been mostly based on laboratory-adapted lines, but there is limited understanding of how these may differ from parasites in natural infections. Loss-of-function mutants have previously been shown to emerge during culture of some Plasmodium falciparum clinical isolates, in analyses that focused on single-genotype infections. The present study included a...

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Literature Corpus work: 411a9960-9ee9-56d1-bec7-b3adc685fafd
DOI: 10.1101/2022.09.14.507918

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