Article

Rapid emergence of clonal interference during malaria parasite cultivation

2020-03-05

Abstract excerpt

Laboratory cultivation of the malaria parasite Plasmodium falciparum has underpinned nearly all advances in malariology in the past 30 years. When freshly isolated clinical isolates are adapted to in vitro culture mutations rapidly fix increasing the parasite growth rate and stability. While the dynamics of culture adaptation are increasingly well characterized, we know little about the extent of genomic variati...

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Literature Corpus work: cdaccab3-37ee-5b14-88b4-9197b95bb7b3
DOI: 10.1101/2020.03.04.977165

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