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Article

The Genotypic and Phenotypic Stability of Plasmodium falciparum Field Isolates in Continuous In Vitro Culture.

PloS one - 1 Jan 2016

Yeda Redemptah, Ingasia Luicer A, Cheruiyot Agnes C, Okudo Charles, Chebon Lorna J, Cheruiyot Jelagat, Akala Hoseah M, Kamau Edwin

Abstract excerpt

The Plasmodium falciparum in vitro culture system is critical for genotypic and phenotypic analyses of the parasites. For genotypic analysis, the genomic DNA can be obtained directly from the patient blood sample or from culture adapted parasites whereas for phenotypic analysis, immediate ex vivo or in vitro culture adapted parasites are used. However, parasite biology studies have not investigated whether...

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PMID: 26751382
DOI: 10.1371/journal.pone.0143565
PMCID: PMC4713440

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