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Article

Association of TLR5 gene polymorphisms in ulcerative colitis patients of north India and their role in cytokine homeostasis.

PloS one - 1 Jan 2015

Meena Naresh Kumar, Ahuja Vineet, Meena Kusumlata, Paul Jaishree

Abstract excerpt

BACKGROUND AND AIM: In health, TLR signaling protects the intestinal epithelial barrier and in disease, aberrant TLR signaling stimulates diverse inflammatory responses. Association of TLR polymorphisms is ethnicity dependent but how they impact the complex pathogenesis of IBD is not clearly defined. So we propose to study the status of polymorphisms in TLR family of genes and their effect on cytokines level in...

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Source

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Identifiers

PMID: 25789623
DOI: 10.1371/journal.pone.0120697
PMCID: PMC4366177

Genes

TLR5
TLR4
TLR1
TLR2
TLR3
TLR6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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