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m6A modification in inflammatory bowel disease provides new insights into clinical applications

25 Jan 2023

Abstract excerpt

Inflammatory bowel disease (IBD) results from a complex interplay between genetic predisposition, environmental factors, and gut microbes. The role of N6-methyladenosine (m6A) methylation in the pathogenesis of IBD has attracted increasing attention. m6A modification not only regulates intestinal mucosal immunity and intestinal barrier function, but also affects apoptosis and autophagy in intestinal epithelial...

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PMID: 36706633
DOI: 10.1016/j.biopha.2023.114298

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