Article

Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer

2022-11-08

Abstract excerpt

Metastatic relapse after treatment is the leading cause of cancer mortality, and known resistance mechanisms are missing for most treatments administered to patients. To bridge this gap, we analyze a pan-cancer cohort (META-PRISM) of 1,031 refractory metastatic tumors profiled via whole-exome and transcriptome sequencing. META-PRISM tumors, particularly prostate, bladder, and pancreatic types, displayed the most t...

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Literature Corpus work: 79a73f96-70f6-5d31-a668-dbeee2c7edba
DOI: 10.1101/2022.11.08.22282064

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