Article

Tcf12 controls dynamic calvarial bone growth and motor learning in mice

2024-01-09

Abstract excerpt

Heterozygous loss-of-function mutations of TCF12 and TWIST1 can each cause craniosynostosis and neurodevelopmental delay in humans. Twist1-Tcf12 interaction plays an important role in regulating suture development. Although the molecular and cellular mechanisms underlying craniosynostosis and neurocognitive dysfunctions in Twist1 +/- mice have been studied, less information on the role of Tcf12 in these defect...

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Literature Corpus work: 40dcadcd-db36-5076-a00c-1076b9c89ab5
DOI: 10.1101/2024.01.09.574781

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