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Article

Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies.

Journal of anatomy - 1 Nov 2005

Morriss-Kay Gillian M, Wilkie Andrew O M

Abstract excerpt

The mammalian skull vault is constructed principally from five bones: the paired frontals and parietals, and the unpaired interparietal. These bones abut at sutures, where most growth of the skull vault takes place. Sutural growth involves maintenance of a population of proliferating osteoprogenitor cells which differentiate into bone matrix-secreting osteoblasts. Sustained function of the sutures as growth...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16313397
DOI: 10.1111/j.1469-7580.2005.00475.x
PMCID: PMC1571561

Genes

EFNB1
FGFR1
FGFR2
FGFR3
MSX2
TWIST1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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