Article

A pan-cancer analysis of the frequency of DNA alterations across cell cycle activity levels

2020-02-25

Abstract excerpt

<h4>Background</h4> Pan-cancer genomic analyses based on the magnitude of pathway activity are currently lacking. Focusing on the cell cycle, we examined the DNA mutations and chromosome arm-level aneuploidy within tumours with low, intermediate and high cell cycle activity. <h4>Patients and methods</h4> Matching mRNA, gene mutational status, chromosomal arm-level aberrations and clinico-pathological data was as...

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Literature Corpus work: 40cf754c-0a2d-5f9f-b57b-9ac5fa82bb27
DOI: 10.1101/2020.02.24.962571

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