Article

Snx14 proximity labeling reveals a role in saturated fatty acid metabolism and ER homeostasis defective in SCAR20 disease

2020-06-01

Abstract excerpt

Fatty acids (FAs) are central cellular metabolites that contribute to lipid synthesis, and can be stored or harvested for metabolic energy. Dysregulation in FA processing and storage causes toxic FA accumulation or altered membrane compositions and contributes to metabolic and neurological disorders. Saturated lipids are particularly detrimental to cells, but how lipid saturation levels are maintained remains poor...

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Identifiers and source

Literature Corpus work: 40b63994-66fe-5411-b320-497cbce7ae32
DOI: 10.1101/2020.05.31.126441

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