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Article

New links between <i>S</i>‐acylation and cancer

24 Feb 2014

Abstract excerpt

S-acylation (also known as palmitoylation) is a major post-translational protein modification in all eukaryotic cells, involving the attachment of fatty acids onto cysteine residues. A variety of structural and signalling proteins are modified in this way, affecting their stability, membrane association and intracellular targeting. The enzymes that mediate S-acylation are encoded by genes belonging to the large...

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PMID: 24615251
DOI: 10.1002/path.4339

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