Article

Evaluation of machine learning methods to predict peptide binding to MHC Class I proteins

2017-06-23

Abstract excerpt

Binding of peptides to Major Histocompatibility Complex (MHC) proteins is a critical step in immune response. Peptides bound to MHCs are recognized by CD8+ (MHC Class I) and CD4+ (MHC Class II) T-cells. Successful prediction of which peptides will bind to specific MHC alleles would benefit many cancer immunotherapy appications. Currently, supervised machine learning is the leading computational approach to predict...

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Identifiers and source

Literature Corpus work: 409d46b5-77d4-53d4-a1dd-7f727fcea401
DOI: 10.1101/154757

Open publication

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