Article

Bayesian meta-analysis across genome-wide association studies of diverse phenotypes

2018-11-24

Abstract excerpt

Genome-wide association studies (GWAS) are a powerful tool for understanding the genetic basis of diseases and traits, but most studies have been conducted in isolation, with a focus on either a single or a set of closely related phenotypes. We describe MetABF, a simple Bayesian framework for performing integrative meta-analysis across multiple GWAS using summary statistics. The approach is applicable across a wid...

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Literature Corpus work: 405fa9a4-5f83-510a-a705-d8c2a4d739e4
DOI: 10.1101/477828

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