Article

Convergent antigenic drift of the influenza hemagglutinin lateral patch across time and species

2026-04-17

Abstract excerpt

The lateral patch epitope of the H1 hemagglutinin (HA) was a dominant target of antibodies following exposure to the 2009 pandemic H1N1 virus. However, the conservation and potential for antigenic drift in the lateral patch remain unresolved. Here, we used lateral patch-specific monoclonal antibodies (mAbs) to understand the antigenicity of the lateral patch of human, avian, and swine H1N x viruses spanning from...

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Literature Corpus work: 4039af68-f91a-544b-9134-3c16ea1b0ed1
DOI: 10.64898/2026.04.16.718966

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