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MANIPULATING MITOCHONDRIAL REACTIVE OXYGEN SPECIES ALTERS SURVIVAL IN UNEXPECTED WAYS IN A <i>DROSOPHILA</i> MODEL OF NEURODEGENERATION

2024-03-29

Abstract excerpt

<h4>ABSTRACT</h4> Reactive oxygen species (ROS) are associated with aging and neurodegeneration, but the significance of this association remains obscure. Here, using a Drosophila model of age-related neurodegeneration, we probe this relationship in the pathologically relevant tissue, the brain, by quantifying three specific mitochondrial ROS and manipulating these redox species pharmacologically. Our goal is to...

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Literature Corpus work: 4012a4c9-c55e-5d06-9da4-cfdda555df9f
DOI: 10.1101/2024.03.25.586603

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MANIPULATING MITOCHONDRIAL REACTIVE OXYGEN SPECIES ALTERS SURVIVAL IN UNEXPECTED WAYS IN A <i>DROSOPHILA</i> MODEL OF NEURODEGENERATIONDOI 10.1101/2024.03.25.586603Read

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