Article

HLA class I peptidome analysis of synthetic long peptide-fed human dendritic cells for therapeutic vaccine design

2024-05-21

Abstract excerpt

<title>Abstract</title> <p>Synthetic long peptides (SLPs) are a promising vaccine modality that exploit dendritic cells (DC) to treat chronic infections or cancer. Currently, the design of SLPs relies on in silico prediction and multifactorial T cells assays to determine which SLPs are best cross-presented on DC human leukocyte antigen class I (HLA-I). Furthermore, it is unknown how TLR ligand-based adjuvants aff...

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Literature Corpus work: 400dacaa-4215-58d1-8c00-10fd5238071e
DOI: 10.21203/rs.3.rs-4384370/v1

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