Article

Pan-cancer NET-associated immunothrombosis coupling identifies a neutrophil-linked but neutrophil-irreducible tumor ecology

2026-07-17

Abstract excerpt

<h4>Background</h4> Neutrophil extracellular traps (NETs) connect innate immunity with thrombosis, metastasis and immune escape, but bulk-tumor NET-associated signatures may mainly report neutrophil abundance. We tested whether an established NETs score also captures a neutrophil-irreducible tumor ecology. <h4>Methods</h4> We reanalysed a published 19-gene NETs score in 9,496 TCGA tumors across 32 cancer types....

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Literature Corpus work: 3fcf50ae-0a45-5bd4-98bf-6b3515b93fa7
DOI: 10.64898/2026.07.14.738403

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