Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor-associated neutrophils in renal cell carcinoma.

Frontiers in immunology - 1 Jan 2026

Kovaleva Olga V, Sinyov Vasiliy V, Rashidova Madina A, Malashenko Olga S, Gratchev Alexei

Abstract excerpt

Renal cell carcinoma (RCC) is an immunogenic tumor in which tumor-associated neutrophils (TANs) and neutrophil extracellular traps (NETs) represent a functionally important component of the tumor microenvironment. Recent studies have revealed pronounced phenotypic heterogeneity of RCC-infiltrating neutrophils, including interferon-responsive, immunosuppressive PMN-MDSC-like, pro-angiogenic, and NET-forming...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Renal Cell
Share to Extracellular Traps
Share to CXCL1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Neoplasms

Share to Molecular Targeted Therapy

Share to Neutrophils

Share to Phenotype

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 41705247
DOI: 10.3389/fimmu.2026.1755401
PMCID: PMC12907418

Genes

CXCL1
CXCL8
PTEN
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor-associated neutrophils in renal cell carcinoma.PMID 41705247Read ↗

Constructing a Neutrophil Extracellular Trap Model Based on Machine Learning to Predict Clinical Outcomes and Immunotherapy Response in Renal Cell CarcinomaSemantic proximity Read ↗

Tumor-associated neutrophils: orchestrating cancer pathobiology and therapeutic resistanceSemantic proximity Read ↗

Identification and validation of the molecular subtype and prognostic signature for clear cell renal cell carcinoma based on neutrophil extracellular trapsSemantic proximity Read ↗

Prognostic value of neutrophil extracellular trap signature in clear cell renal cell carcinomaSemantic proximity Read ↗

Neutrophil Heterogeneity in Cancer: From Biology to TherapiesSemantic proximity Read ↗

Two-Faced Roles of Tumor-Associated Neutrophils in Cancer Development and ProgressionSemantic proximity Read ↗

Deterministic reprogramming of neutrophils within tumorsSemantic proximity Read ↗

Neutrophil extracellular traps in cancerSemantic proximity Read ↗

Roles of neutrophils in cancer growth and progressionSemantic proximity Read ↗

Neutrophils: Orchestrators of the Malignant Phenotype.Semantic proximity Read ↗

Tumor‑associated neutrophils: Critical regulators in cancer progression and therapeutic resistance (Review)Semantic proximity Read ↗

CD61 + LDNs drive cancer metastasis by upregulating CCDC25 expression via DNA-TLR9-NF-kB axis in HCCSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.