Article

Whole-genome DNA methylomes of Tree shrew brains reveal conserved and divergent roles of DNA methylation on sex chromosome regulation

2024-06-08

Abstract excerpt

The tree shrew ( Tupaia belangeri ) is a promising emerging model organism in biomedical studies, notably due to their evolutionary proximity to primates. To enhance our understanding of how DNA methylation is implicated in regulation of gene expression and the X chromosome inactivation (XCI) in tree shrew brains, here we present their first genome-wide, single-base-resolution methylomes integrated with transcrip...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3fb351e0-cb6e-52e9-ad7b-588294a47b2f
DOI: 10.1101/2024.06.05.597676

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole-genome DNA methylomes of Tree shrew brains reveal conserved and divergent roles of DNA methylation on sex chromosome regulationDOI 10.1101/2024.06.05.597676Read

Cross-species examination of X-chromosome inactivation highlights domains of escape from silencingSemantic proximity Read

Chromosome-wide profiling of X-chromosome inactivation and epigenetic states in fetal brain and placenta of the opossum, Monodelphis domestica.Semantic proximity Read

DNA methylation differences between the female and male X chromosomes in human brainSemantic proximity Read

Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropodsSemantic proximity Read

Differential DNA methylation of vocal and facial anatomy genes in modern humans.Semantic proximity Read

X-Chromosome Inactivation and Escape from X Inactivation in Mouse.Semantic proximity Read

DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic ageingSemantic proximity Read

Genes Affecting Vocal and Facial Anatomy Went Through Extensive Regulatory Divergence in Modern HumansSemantic proximity Read

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation.Semantic proximity Read

Landscape of X chromosome inactivation across human tissues.Semantic proximity Read

Extensive remodelling of <i>XIST</i> regulatory networks during primate evolutionSemantic proximity Read