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Prostaglandin I2 signaling prevents angiotensin II-induced atrial remodeling and vulnerability to atrial fibrillation in mice

2024-06-26

Abstract excerpt

<title>Abstract</title> <p>Atrial fibrillation (AF) is the most common arrhythmia, and atrial fibrosis is a pathological hallmark of structural remodeling in AF. Prostaglandin I<sub>2</sub> (PGI<sub>2</sub>) can prevent the process of fibrosis in various tissues via cell surface Prostaglandin I<sub>2</sub> receptor (IP). However, the role of PGI<sub>2</sub> in AF and atrial fibrosis remains unclear. The present s...

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Literature Corpus work
3f61a6f2-f9b5-5b36-b1c4-216cad7813f3
DOI
10.21203/rs.3.rs-4539461/v1
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Prostaglandin I2 signaling prevents angiotensin II-induced atrial remodeling and vulnerability to atrial fibrillation in miceDOI 10.21203/rs.3.rs-4539461/v1
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