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Article

The inflammation-resolution promoting molecule resolvin-D1 prevents atrial proarrhythmic remodelling in experimental right heart disease.

Cardiovascular research - 16 Jun 2021

Hiram Roddy, Xiong Feng, Naud Patrice, Xiao Jiening, Sirois Martin, Tanguay Jean-François, Tardif Jean-Claude, Nattel Stanley

Abstract excerpt

AIMS: Inflammation plays a role in atrial fibrillation (AF), but classical anti-inflammatory molecules are ineffective. Recent evidence suggests that failure of inflammation-resolution causes persistent inflammatory signalling and that a novel drug-family called resolvins promotes inflammation-resolution. Right heart disease (RHD) is associated with AF; experimental RHD shows signs of atrial inflammatory-pathway...

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Identifiers

PMID: 32866246
DOI: 10.1093/cvr/cvaa186
PMCID: PMC8208753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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