Article

Single-nucleus detection of rare HIV-infected cells defines the cellular landscape of HIV persistence in the human brain

2026-03-10

Abstract excerpt

<title>Abstract</title> <p>Background HIV-1 enters the central nervous system early after infection and establishes a long-lived reservoir that persists despite antiretroviral therapy. Single-cell and single-nucleus RNA sequencing provide powerful approaches to study HIV infection in the human brain, yet standardized and sensitive methods for identifying rare HIV-infected cells in these datasets remain limited....

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Literature Corpus work: 3f3256e1-d0f3-5d5b-9fdb-22597643f9db
DOI: 10.21203/rs.3.rs-9013592/v1

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