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HIV-1 RNA in extracellular vesicles is associated with neurocognitive outcomes

23 May 2024

Abstract excerpt

Human immunodeficiency virus type-1 (HIV-1) is responsible for significant mortality and morbidity worldwide. Despite complete control of viral replication with antiretrovirals, cells with integrated HIV-1 provirus can produce viral transcripts. In a cross-sectional study of 84 HIV+ individuals of whom 43 were followed longitudinally, we found that HIV-1 RNAs are present in extracellular vesicles (EVs) derived...

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PMID: 38782925
DOI: 10.1038/s41467-024-48644-z

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