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Natural polymorphisms in Pseudomonas aeruginosa populations reveal a dual role for DNA gyrase in fluoroquinolone resistance and persistence

2025-08-22

Abstract excerpt

<title>Abstract</title> <p>A genetic atlas of bacterial antibiotic survival could inform clinical decisions offering novel therapeutic options and improving treatment success. While antibiotic resistance is well-studied, persistence remains poorly understood, particularly in the context of the vast natural strain diversity among pathogens. Here, we investigated both phenotypes in over 350 diverse, natural isolate...

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Literature Corpus work
3f140887-12ed-5a56-bb52-d855ecd22db5
DOI
10.21203/rs.3.rs-7146623/v1
Open publication

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Natural polymorphisms in Pseudomonas aeruginosa populations reveal a dual role for DNA gyrase in fluoroquinolone resistance and persistenceDOI 10.21203/rs.3.rs-7146623/v1
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