Heterogeneous dynamics of mobile genetic elements encode and spread antibiotic persistence in bacteria

Abstract excerpt

Bacterial persisters are nonreplicating cells that transiently evade antibiotic killing within an otherwise susceptible, replicating population. While persister formation has traditionally been attributed to phenotypic heterogeneity, reversible functional variations among genetically identical cells, most studies lack direct genomic evidence to exclude the contribution of cryptic and reversible genetic variations....

Topics

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• Anti-Bacterial Agents
• Bacteria
• Bacterial Infections
• Drug Resistance, Bacterial
• Evolution, Molecular
• Gene Expression
• Genetic Variation
• Models, Biological

Identifiers and source

Literature Corpus work

673e4072-8917-578a-895e-a3b073ffd432

DOI

10.64898/2026.02.27.708469