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Advances in B‐cell Precursor Acute Lymphoblastic Leukemia Genomics

17 Jun 2018

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Abstract In childhood B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL), cytogenetic abnormalities remain important diagnostic and prognostic tools. A number of well‐established abnormalities are routinely used in risk stratification for treatment. These include high hyperdiploidy and ETV6‐RUNX1 fusion, classified as good risk, while Philadelphia chromosome (Ph) positive ALL and rearrangements of the KMT2A...

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PMID: 31723781
DOI: 10.1097/hs9.0000000000000053

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