Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia.

Frontiers of medicine - 1 Jun 2021

Li Jianfeng, Dai Yuting, Wu Liang, Zhang Ming, Ouyang Wen, Huang Jinyan, Chen Saijuan

Abstract excerpt

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by genetic alterations with high heterogeneity. Precise subtypes with distinct genomic and/or gene expression patterns have been recently revealed using high-throughput sequencing technology. Most of these profiles are associated with recurrent non-overlapping rearrangements or hotspot point mutations that are analogous to the established...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Mutation
Share to Oncogene Proteins, Fusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 33400146
DOI: 10.1007/s11684-020-0821-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia.PMID 33400146Read ↗

Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 casesSemantic proximity Read ↗

New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemiaSemantic proximity Read ↗

Identification of Molecular Subtypes of B-Cell Acute Lymphoblastic Leukemia in Mexican Children by Whole-Transcriptome Analysis.Semantic proximity Read ↗

Genetic subtypes of B-cell acute lymphoblastic leukemia in adultsSemantic proximity Read ↗

Oncogenic lesions and molecular subtypes in adults with B-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

Advances in B‐cell Precursor Acute Lymphoblastic Leukemia GenomicsSemantic proximity Read ↗

Utility of a Large Series of B‐Cell Precursor Acute Lymphoblastic Leukemia Cell Lines as a Model SystemSemantic proximity Read ↗

Advances in the diagnosis and classification of B-ALL: comparative insights from updated guidelines.Semantic proximity Read ↗

Molecular Characterization of Pediatric B-cell Acute Lymphoblastic Leukemia using Integrative Transcriptomics: A Multicenter Study in ArgentinaSemantic proximity Read ↗

Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohortSemantic proximity Read ↗

Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma.Semantic proximity Read ↗

PAX5 alterations in B-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.