Article
A novel tool for monitoring endogenous human MYC transcription and translation by EGFP tag insertion at the 3’ end using CRISPR-Cas9 genome editing
2019-04-09
Abstract excerpt
The MYC oncogene is overexpressed in over 70% of human cancers. Since its identification, the study of MYC has led to the discovery of the various ways through which oncogenes contribute to the ability of normal cells to become malignant. However, there are many aspects of MYC biology that remain unknown or controversial in terms of its regulation, targetability and downstream control of its targets. We developed...
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Identifiers and source
- Literature Corpus work
- 3eb666e3-8c55-556c-9edf-c0ee13e5bdf8
- DOI
- 10.1101/603746