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Article

Strategies to target the cancer driver MYC in tumor cells

8 Mar 2023

Abstract excerpt

The MYC oncoprotein functions as a master regulator of cellular transcription and executes non-transcriptional tasks relevant to DNA replication and cell cycle regulation, thereby interacting with multiple proteins. MYC is required for fundamental cellular processes triggering proliferation, growth, differentiation, or apoptosis and also represents a major cancer driver being aberrantly activated in most human...

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Identifiers

PMID: 36969025
DOI: 10.3389/fonc.2023.1142111

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