Article

Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa

2021-01-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> HIV-1C has been shown to have a greater risk of virological failure and reduced susceptibility towards boosted protease inhibitors (bPIs), a component of second-line combination antiretroviral therapy (cART) in South Africa. This study entailed an evaluation of HIV-1 drug resistance-associated mutations (RAMs) among minor viral populations through high-throughpu...

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Literature Corpus work: 3ea971b5-c217-506e-aa1f-a646dad1c96b
DOI: 10.21203/rs.3.rs-32105/v2

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