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High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa

27 Jul 2017

Abstract excerpt

BACKGROUND: Combination antiretroviral therapy (cART) has significantly reduced HIV morbidity and mortality in both developed and developing countries. However, the sustainability of cART may be compromised by the emergence of viral drug resistance mutations (DRM) and the cellular persistence of proviruses carrying these DRM. This is potentially a more serious problem in resource limited settings. METHODS: DRM...

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PMID: 28750647
DOI: 10.1186/s12981-017-0161-z

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