Article
Drug Resistance Mutations in a Population Before Antiretroviral Therapy Initiation in Northern South Africa.
AIDS research and human retroviruses - 1 Mar 2022
Ogola Bixa, Matume Nontokozo D, Mavhandu-Ramarumo Lufuno G, Tebit Denis M, Bessong Pascal O
Abstract excerpt
South Africa introduced the "diagnose and treat" universal HIV treatment program in September 2016. This program enables all identified HIV-positive patients to immediately start first-line antiretroviral therapy (ART). However, the presence of drug-resistant (DR) viruses in the drug-naive population complicates the choice of ART. We used next-generation sequencing (NGS) to determine the prevalence and diversity...
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