Article

SHIMS 3.0: Highly efficient single-haplotype iterative mapping and sequencing using ultra-long nanopore reads

2020-09-20

Abstract excerpt

The reference sequence of structurally complex regions can only be obtained through a highly accurate clone-based approach that we call Single-Haplotype Iterative Mapping and Sequencing (SHIMS). In recent years, improvements to SHIMS have reduced the cost and time required by two orders of magnitude, but internally repetitive clones still require extensive manual effort to transform draft assemblies into reference...

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Literature Corpus work: 3ea557df-1313-57d2-82a7-7fb01a45081a
DOI: 10.1101/2020.09.18.303735

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