Article

Cost-effective, high-throughput, single-haplotype iterative mapping and sequencing for complex genomic structures

2017-06-29

Abstract excerpt

Reference sequence of structurally complex regions can only be obtained through highly accurate clone-based approaches. We and others have successfully employed Single-Haplotype Iterative Mapping and Sequencing (SHIMS 1.0) to assemble structurally complex regions across the sex chromosomes of several vertebrate species and in targeted improvements to the reference sequences of human autosomes. However, SHIMS 1.0 w...

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Literature Corpus work: 8ec86139-9c35-5daf-a6ac-6600b5d6be58
DOI: 10.1101/157206

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