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Article

<i>Glial swip-10</i> expression controls systemic mitochondrial function, oxidative stress, and neuronal viability via copper ion homeostasis

2023-12-08

Abstract excerpt

Cuprous copper (Cu(I)) is an essential cofactor for enzymes supporting many cellular functions including mitochondrial respiration and suppression of oxidative stress. Neurons are particularly dependent on these pathways, with multiple neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease, associated with their dysfunction. Key features of Cu(I) contributions to neuronal health in vi...

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Literature Corpus work
3e924d6b-dfdd-59f7-9068-3666ce90dabe
DOI
10.1101/2023.12.06.570462
Open publication

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<i>Glial swip-10</i> expression controls systemic mitochondrial function, oxidative stress, and neuronal viability via copper ion homeostasisDOI 10.1101/2023.12.06.570462
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