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Article

Copper-mediated neurotoxicity and genetic vulnerability in the background of neurodegenerative diseases in C. elegans.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Oct 2024

Weishaupt Ann-Kathrin, Ruecker Lysann, Meiners Torben, Schwerdtle Tanja, Silva Avila Daiana, Aschner Michael, Bornhorst Julia

Abstract excerpt

The mechanisms associated with neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD), have yet to be fully characterized, and genetic as well as environmental factors in their disease etiology are underappreciated. Although mutations in genes such as PARKIN and LRRK2 have been linked to PD, the idiopathic component of the disease suggests a contribution of environmental risk...

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PMID: 39067045
DOI: 10.1093/toxsci/kfae092
PMCID: PMC11424883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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