Article
MeCP2 controls dendritic morphogenesis via miR-199a-mediated Qki downregulation
2025-04-05
Abstract excerpt
Rett syndrome (RTT) (OMIM: 312750) is a severe neurodevelopmental disorder caused by mutations in the MECP2 gene. Although decreased dendritic morphogenesis has been observed in the brain of RTT patients and mouse models, the molecular mechanisms underlying these dendritic anomalies remain unclear. We have previously shown that MeCP2 facilitates specific microRNA (miRNA) processing by associating with the miRNA m...
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Identifiers and source
- Literature Corpus work
- 3e4545ff-6c03-5890-9912-2370e077dd07
- DOI
- 10.1101/2025.04.04.642981
