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Article

MeCP2 controls dendritic morphogenesis via miR-199a-mediated Qki downregulation

2025-04-05

Abstract excerpt

Rett syndrome (RTT) (OMIM: 312750) is a severe neurodevelopmental disorder caused by mutations in the MECP2 gene. Although decreased dendritic morphogenesis has been observed in the brain of RTT patients and mouse models, the molecular mechanisms underlying these dendritic anomalies remain unclear. We have previously shown that MeCP2 facilitates specific microRNA (miRNA) processing by associating with the miRNA m...

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Literature Corpus work
3e4545ff-6c03-5890-9912-2370e077dd07
DOI
10.1101/2025.04.04.642981
Open publication

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MeCP2 controls dendritic morphogenesis via miR-199a-mediated Qki downregulationDOI 10.1101/2025.04.04.642981
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