Article

Asthma exacerbations and eosinophilia in the UK Biobank: a Genome-Wide Association Study

2023-04-19

Abstract excerpt

Asthma exacerbations reflect disease severity, affect morbidity and mortality, and may lead to declining lung function. Inflammatory endotypes (e.g.:T2-high (eosinophilic)) may play a key role in asthma exacerbations. We aimed to assess whether genetic susceptibility underlies asthma exacerbation risk and additionally tested for an interaction between genetic variants and eosinophilia on exacerbation risk. UK Biob...

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Literature Corpus work: 3e3a96e6-cb4f-5b0f-a7c6-bbf9db870f06
DOI: 10.1101/2023.04.12.23288479

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