Article

A broad exome study of the genetic architecture of asthma reveals novel patient subgroups

2020-12-11

Abstract excerpt

<h4>Introduction</h4> Asthma risk is a complex interplay between genetic susceptibility and environment. Despite many significantly-associated common variants, the contribution of rarer variants with potentially greater effect sizes has not been as extensively studied. We present an exome-based study adopting 24,576 cases and 120,530 controls to assess the contribution of rare protein-coding variants to the risk...

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Literature Corpus work: cda9ff00-bb0e-5587-b984-fb6a5773c4d6
DOI: 10.1101/2020.12.10.419663

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