Article

Tryptophanyl-tRNA synthetase-1 (WARS1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegans

2023-11-07

Abstract excerpt

<title>Abstract</title> The fidelity of translation is ensured by a family of proteins named aminoacyl-tRNA synthetases, making them crucial for development and survival. More recently, mutations in the tryptophanyl-tRNA synthetase (<italic>WARS1</italic>) have been linked to various human diseases, from intellectual disability to various types of cancer. To understand the function of WARS1, we investigated th...

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Literature Corpus work: 3dfd7be8-95f2-5b34-b05a-6611a29d1ba9
DOI: 10.21203/rs.3.rs-3405652/v1

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Tryptophanyl-tRNA synthetase-1 (WARS1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegansDOI 10.21203/rs.3.rs-3405652/v1Read

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