Article
Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 22 Jan 2014
Xu Xiaoxiao, Wells Alan B, O'Brien David R, Nehorai Arye, Dougherty Joseph D
Abstract excerpt
Recent advances have substantially increased the number of genes that are statistically associated with complex genetic disorders of the CNS such as autism and schizophrenia. It is now clear that there will likely be hundreds of distinct loci contributing to these disorders, underscoring a remarkable genetic heterogeneity. It is unclear whether this genetic heterogeneity indicates an equal heterogeneity of...
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