Article

Immune Imprinting with Ancestral SARS-CoV-2 Strain Induced Potent Neutralizing Activity Against Omicron Sublineages BA.2, BA.2.12.1 and BA.4/5

2022-09-01

Abstract excerpt

Background: Immune imprinting plays a crucial role in subsequent antibody responses against SARS-CoV-2. However, unknown prior exposures due to subclinical infections may confound the results. With a low prevalence of COVID-19 before 2022 (<0.2% of the population), the chance of unknown prior SARS-CoV-2 exposure is low in Hong Kong, which provides a unique opportunity to accurately delineate the importance immune...

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Literature Corpus work: 3db00e42-06d0-5015-9b08-fa34508db06b
DOI: 10.2139/ssrn.4206824

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