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Article

Immunological imprinting of humoral immunity to SARS-CoV-2 in children

29 Jun 2023

Abstract excerpt

Omicron variants of SARS-CoV-2 are globally dominant and infection rates are very high in children. We measure immune responses following Omicron BA.1/2 infection in children aged 6-14 years and relate this to prior and subsequent SARS-CoV-2 infection or vaccination. Primary Omicron infection elicits a weak antibody response with poor functional neutralizing antibodies. Subsequent Omicron reinfection or COVID-19...

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PMID: 37386081
DOI: 10.1038/s41467-023-39575-2

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