Article

The anti-atherosclerosis effect of anakinra, a recombinant human interleukin-1 receptor antagonist, in apolipoprotein E knockout mice

2021-06-12

Abstract excerpt

<title>Abstract</title> <bold>Purpose </bold>Interleukin (IL)-1β plays an important role in the atherosclerosis pathogenesis. We aimed to investigate the effect of anakinra, a recombinant human IL-1 receptor antagonist, on the progression of atherosclerosis in apolipoprotein E knockout (ApoE−/−) mice.<bold>Methods </bold>ApoE−/− mice (8-week male) were treated with saline (control), anaki...

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Literature Corpus work: 3d8f3aff-a48e-5643-8a88-dbb140a31a1f
DOI: 10.21203/rs.3.rs-482370/v1

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