Article
Ultrasound Biomicroscopic Imaging for Interleukin-1 Receptor Antagonist-Inhibiting Atherosclerosis and Markers of Inflammation in Atherosclerotic Development in Apolipoprotein-E Knockout Mice.
Texas Heart Institute journal - 1 Aug 2015
Li Rong-Juan, Sun Yan, Wang Qin, Yang Jiao, Yang Ya, Song Li, Wang Zheng, Luo Xiang-Hong, Su Rui-Juan
Abstract excerpt
We sought to validate the hypothesis that the development of atherosclerosis can be suppressed by the interleukin-1 receptor antagonist (IL-1Ra) in murine models of atherosclerosis in vivo, noninvasively seen by means of high-resolution ultrasound biomicroscopy, and we studied changes in inflammatory markers such as IL-1 and C-reactive protein (CRP) plasma levels in these models of atherosclerosis. We divided...
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