Article

The polyol pathway is a crucial glucose sensor in <i>Drosophila</i>

2020-03-17

Abstract excerpt

<h4>Summary</h4> A major nutrient source for animals is glucose, which induces transcriptional responses that shift metabolism. Such metabolic adaptation should be appropriately scaled to the ingested glucose levels, and decoupling causes human metabolic diseases. However, the identity of the crucial sensor metabolite(s) that transmit circulating glucose levels to the transcriptional machinery remains elusive. He...

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Literature Corpus work: d42313c8-7318-5dca-be57-6c65517c8dfb
DOI: 10.1101/2020.03.16.993170

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