Article

Chromosome 7 to the rescue: overcoming chromosome 10 loss in gliomas

2024-01-22

Abstract excerpt

<h4>ABSTRACT</h4> The co-occurrence of chromosome 10 loss and chromosome 7 gain in gliomas is the most frequent loss-gain co-aneuploidy pair in human cancers, a phenomenon that has been investigated without resolution since the late 1980s. Expanding beyond previous gene-centric studies, we investigate the co-occurrence in a genome-wide manner taking an evolutionary perspective. First, by mining large tumor aneupl...

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Literature Corpus work: 3d82da96-890c-50f0-8ec4-1402e4295a18
DOI: 10.1101/2024.01.17.576103

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