Article
WHO grade-specific comparative genomic hybridization pattern of astrocytoma - a meta-analysis.
Pathology, research and practice - 15 Oct 2010
Holland Heidrun, Koschny Thomas, Ahnert Peter, Meixensberger Jürgen, Koschny Ronald
Abstract excerpt
To detect novel genetic alterations, many astrocytomas have been investigated by comparative genomic hybridization (CGH). To identify aberration profiles characteristic of World Health Organization (WHO) grade I, II, III, and IV astrocytoma, we performed a meta-analysis of detailed genome wide CGH data of all 467 cases published so far. After expansion of all given aberrations to the maximum of 850 GTG-band...
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